Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618272 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8551529 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8546589 | 0.78 | NPY1R (0.33) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10691483 | 0.76 | FFAR1 (0.58) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10691175 | 0.74 | TSHR (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10689934 | 0.73 | LMNA (0.40) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10685537 | 0.71 | TSHR (0.39) | ALDH1A1MAPTLMNAMAPK1POLB | |
| SCHEMBL18256147 | 0.67 | GAA (0.43) | ALDH1A1MAPTLMNAPOLBKDM4E | |
| SCHEMBL8549566 | 0.66 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8549735 | 0.66 | MAPT (0.35) | ALDH1A1MAPTLMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |