Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551235 | 0.86 | ALDH1A1 (0.39) | MAPTPKMKDM4EALDH1A1LMNA | |
| SCHEMBL8673850 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10689934 | 0.76 | LMNA (0.40) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL8546628 | 0.72 | ALDH1A1 (0.42) | MAPTPKMKDM4EALDH1A1NPC1 | |
| SCHEMBL8666788 | 0.71 | TRPM8 (0.41) | MAPTPKMKDM4EALDH1A1LMNA | |
| SCHEMBL8545150 | 0.69 | GAA (0.43) | MAPTPKMKDM4EALDH1A1LMNA | |
| SCHEMBL8548183 | 0.69 | SMN1; SMN2 (0.43) | KDM4EALDH1A1LMNANPC1HPGD | |
| SCHEMBL8551379 | 0.68 | KDM4E (0.49) | MAPTPKMKDM4EALDH1A1LMNA | |
| SCHEMBL7070155 | 0.68 | KDM4E (0.46) | MAPTPKMKDM4EALDH1A1LMNA | |
| SCHEMBL4548034 | 0.68 | MAPT (0.59) | MAPTPKMKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |