Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | FPR1 | P21462 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550650 | 0.89 | FPR1 (0.53) | LMNAFPR1GAASLCO1B1L3MBTL1 | |
| SCHEMBL8554704 | 0.86 | CA1 (0.43) | FPR1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL8556018 | 0.85 | LMNA (0.48) | LMNAFPR1GAASLCO1B1L3MBTL1 | |
| SCHEMBL8555343 | 0.85 | FPR1 (0.50) | LMNAFPR1GAASLCO1B1L3MBTL1 | |
| SCHEMBL8555582 | 0.85 | LMNA (0.47) | LMNAFPR1GAASLCO1B1L3MBTL1 | |
| SCHEMBL8555845 | 0.85 | LMNA (0.47) | LMNAPTGESALOX5FPR1GAA | |
| SCHEMBL8552811 | 0.82 | FPR1 (0.45) | LMNAFPR1GAASLCO1B1L3MBTL1 | |
| SCHEMBL1984012 | 0.81 | NTRK1 (0.48) | LMNAPTGESALOX5FPR1SLCO1B1 | |
| SCHEMBL8555862 | 0.81 | NTRK1 (0.48) | LMNAFPR1GAASLCO1B1KMT2A | |
| SCHEMBL8552919 | 0.81 | FPR1 (0.44) | LMNAPTGESALOX5FPR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |