Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 8/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550650 | 0.92 | FPR1 (0.53) | NTRK1POLBHTTKMT2AALDH1A1 | |
| SCHEMBL1984012 | 0.90 | NTRK1 (0.48) | NTRK1POLBHTTMAPTALDH1A1 | |
| SCHEMBL8552895 | 0.88 | FPR1 (0.48) | NTRK1POLBHTTMAPTALDH1A1 | |
| SCHEMBL8551653 | 0.84 | NTRK1 (0.53) | NTRK1POLBHTTMAPTALDH1A1 | |
| SCHEMBL8557247 | 0.84 | NTRK1 (0.51) | NTRK1POLBHTTMAPTALDH1A1 | |
| SCHEMBL8553012 | 0.81 | LMNA (0.49) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8556018 | 0.80 | LMNA (0.48) | NTRK1KMT2AALDH1A1FPR1SLCO1B1 | |
| SCHEMBL8555343 | 0.80 | FPR1 (0.50) | NTRK1KMT2AALDH1A1FPR1SLCO1B1 | |
| SCHEMBL8555845 | 0.80 | LMNA (0.47) | NTRK1KMT2AALDH1A1FPR1SLCO1B1 | |
| SCHEMBL8555582 | 0.80 | LMNA (0.47) | NTRK1MAPTKMT2AALDH1A1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |