Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 7/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | AGER | Q15109 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552606 | 0.90 | DGAT2 (0.43) | DGAT2NPY1RHRH2HRH1LMNA | |
| SCHEMBL7686453 | 0.89 | DGAT2 (0.44) | DGAT2NPY1RCHEK2 | |
| SCHEMBL8556963 | 0.89 | DGAT2 (0.41) | DGAT2NPY1RLMNA | |
| SCHEMBL8555907 | 0.87 | CHEK2 (0.43) | DGAT2CHEK2 | |
| SCHEMBL8555463 | 0.86 | GPR119 (0.40) | DGAT2NPY1RCHEK2 | |
| SCHEMBL8555211 | 0.81 | GPR119 (0.45) | DGAT2NPY1RCHEK2 | |
| SCHEMBL8555848 | 0.80 | DGAT2 (0.39) | DGAT2CHEK2 | |
| SCHEMBL8554479 | 0.79 | NPY1R (0.45) | DGAT2NPY1RHRH2HRH1LMNA | |
| SCHEMBL8620953 | 0.79 | DGAT2 (0.41) | DGAT2NPY1RCHEK2HRH3 | |
| SCHEMBL8552592 | 0.79 | GPR119 (0.39) | DGAT2NPY1RCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |