Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.43 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118468 | 0.91 | KCNA5 (0.45) | KCNA5KCND3SLC6A4CYP3A4CYP3A5 | |
| SCHEMBL8117056 | 0.87 | CYP3A4 (0.40) | KCNA5KCND3CYP3A4CYP3A5CYP17A1 | |
| SCHEMBL8552624 | 0.87 | CYP19A1 (0.47) | KCNA5CYP3A4CYP17A1ADRB3ADRB1 | |
| SCHEMBL8109544 | 0.87 | SMN1; SMN2 (0.44) | KCNA5SLC6A4CYP3A4CYP17A1ADRB3 | |
| SCHEMBL8552960 | 0.86 | MARS1 (0.41) | SLC6A4CYP3A4CYP3A5CYP17A1CYP19A1 | |
| SCHEMBL8133883 | 0.85 | CYP17A1 (0.40) | KCNA5SLC6A4CYP3A4CYP17A1ADRB3 | |
| SCHEMBL8124227 | 0.84 | CYP19A1 (0.39) | KCNA5CYP3A4CYP17A1ADRB3ADRB1 | |
| SCHEMBL8552459 | 0.83 | CYP17A1 (0.44) | CYP3A4CYP17A1ADRB3ADRB1CYP19A1 | |
| SCHEMBL8118689 | 0.82 | KCNA5 (0.48) | KCNA5CYP3A4CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL8118264 | 0.82 | DGAT2 (0.39) | KCNA5CYP3A4CYP17A1ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |