Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103998 | 0.82 | HRH3 (0.43) | HRH3TPSAB1LMNAKMT2ALSS | |
| SCHEMBL8104006 | 0.79 | TPSAB1 (0.41) | HRH3TPSAB1LMNAKMT2ALSS | |
| SCHEMBL8550694 | 0.77 | MEN1 (0.48) | LMNAKMT2AALDH1A1MEN1HTT | |
| SCHEMBL8103946 | 0.72 | LMNA (0.58) | LMNAKMT2AALDH1A1MEN1HTT | |
| SCHEMBL8096415 | 0.71 | MMP12 (0.45) | LMNAPOLBRAB9AMMP1MMP13 | |
| SCHEMBL9566226 | 0.65 | LMNA (0.50) | LMNAKMT2APOLBHTTRAB9A | |
| Hydrochloric Acid SCHEMBL8701160 | 0.64 | LMNA (0.49) | LMNAKMT2APOLBHTTRAB9A | |
| SCHEMBL8096541 | 0.64 | FAAH (0.51) | KMT2A | |
| SCHEMBL4674825 | 0.64 | KMT2A (0.57) | HRH3LMNAKMT2AALDH1A1POLB | |
| SCHEMBL4674822 | 0.64 | KMT2A (0.57) | HRH3LMNAKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |