Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551240 | 0.82 | SMN1; SMN2 (0.44) | TBXAS1SMN1; SMN2PDE4DLMNAL3MBTL1 | |
| SCHEMBL8554087 | 0.81 | KCNA5 (0.46) | SMN1; SMN2PDE4DLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11708267 | 0.75 | ALDH1A1 (0.49) | TBXAS1EPHX2CYP2C9CYP2C19GRM2 | |
| SCHEMBL2403430 | 0.74 | LMNA (0.58) | GRM2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8775798 | 0.73 | SMN1; SMN2 (0.58) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8555644 | 0.73 | CYP3A4 (0.44) | CYP2C9SMN1; SMN2PDE4DLMNAL3MBTL1 | |
| SCHEMBL29057338 | 0.73 | ALDH1A1 (0.53) | SMN1; SMN2LMNANPC1ALDH1A1RAB9A | |
| SCHEMBL1944201 | 0.73 | CFTR (0.59) | TBXAS1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8551012 | 0.72 | PDE4D (0.47) | CYP2C9PDE4DNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL5999698 | 0.71 | CFTR (0.57) | TBXAS1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |