Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667814 | 0.89 | HTR2B (0.34) | CNR2USP2CACNA1DHTR2BHTR6 | |
| SCHEMBL8552344 | 0.87 | S1PR1 (0.30) | CNR2 | |
| SCHEMBL8551858 | 0.87 | NCF1 (0.34) | PPARGRXRANR1H3NCF1 | |
| SCHEMBL8547167 | 0.85 | TDP1 (0.41) | PPARGRXRANR1H3NCF1PIK3CA | |
| SCHEMBL8550783 | 0.83 | USP2 (0.34) | CNR2USP2CACNA1DHTR2BHTR6 | |
| SCHEMBL8550417 | 0.83 | RXRA (0.34) | PPARGRXRANR1H3CNR2USP2 | |
| SCHEMBL8550349 | 0.83 | KDM4E (0.42) | NCF1ALDH1A1 | |
| SCHEMBL8672813 | 0.83 | CXCR3 (0.34) | USP2HTR2BHTR6PTGDR2 | |
| SCHEMBL8552341 | 0.81 | PDE2A (0.33) | RXRACNR2USP2CACNA1DHTR2B | |
| SCHEMBL8550780 | 0.79 | RXRA (0.37) | PPARGRXRANR1H3CNR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |