Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667811 | 0.89 | CACNA1D (0.36) | CACNA1DCNR2PTGDR2USP2 | |
| SCHEMBL8552335 | 0.88 | CACNA1D (0.33) | CACNA1DPTGDR2 | |
| SCHEMBL8551852 | 0.88 | NCF1 (0.33) | RXRAPPARGNR1H3POLBNCF1 | |
| SCHEMBL8547164 | 0.85 | TDP1 (0.38) | RXRAPPARGNR1H3NCF1 | |
| SCHEMBL8551375 | 0.83 | KDM4E (0.39) | POLBL3MBTL1NCF1 | |
| SCHEMBL8550785 | 0.79 | PPARG (0.36) | RXRAPPARGNR1H3CACNA1DCNR2 | |
| SCHEMBL8553294 | 0.73 | S1PR4 (0.33) | — | |
| SCHEMBL8550417 | 0.73 | RXRA (0.34) | RXRAPPARGNR1H3CACNA1DCNR2 | |
| SCHEMBL8672349 | 0.73 | TLR8 (0.39) | — | |
| SCHEMBL8668302 | 0.72 | CACNA1D (0.35) | CACNA1DCNR2PTGDR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |