Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549536 | 0.86 | NPC1 (0.54) | ALDH1A1LMNAKMT2ARAB9AMAPT | |
| SCHEMBL28975789 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAKMT2AHSP90AA1 | |
| SCHEMBL23280913 | 0.81 | HTT (0.56) | ALDH1A1LMNARAB9AHTTNPC1 | |
| SCHEMBL15146792 | 0.80 | HTT (0.68) | ALDH1A1SMN1; SMN2LMNARAB9AHTT | |
| SCHEMBL966936 | 0.79 | HTT (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AHSP90AA1 | |
| SCHEMBL966937 | 0.79 | HTT (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AHSP90AA1 | |
| SCHEMBL6202818 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAKMT2AHSP90AA1 | |
| SCHEMBL3381007 | 0.76 | HTT (0.57) | ALDH1A1LMNARAB9AHTTHPGD | |
| SCHEMBL10358851 | 0.76 | HTT (0.57) | ALDH1A1LMNARAB9AHTTHPGD | |
| SCHEMBL28975797 | 0.74 | PIN1 (0.43) | ALDH1A1SMN1; SMN2LMNAKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |