Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550795 | 0.86 | ALDH1A1 (0.54) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL23280913 | 0.81 | HTT (0.56) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL15146792 | 0.80 | HTT (0.68) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL10358851 | 0.79 | HTT (0.57) | ALDH1A1RAB9AHPGDHTTLMNA | |
| SCHEMBL3381007 | 0.79 | HTT (0.57) | ALDH1A1RAB9AHPGDHTTLMNA | |
| SCHEMBL28975790 | 0.75 | RAB9A (0.51) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL27555268 | 0.74 | CTRB1 (0.53) | NPC1ALDH1A1RAB9AHTTLMNA | |
| SCHEMBL7223871 | 0.74 | TAS1R3 (0.63) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL11018467 | 0.74 | HTT (0.60) | NPC1ALDH1A1RAB9AHPGDHTT | |
| SCHEMBL28975789 | 0.74 | ALDH1A1 (0.49) | NPC1ALDH1A1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |