Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481177 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL8476796 | 0.87 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTHTTNAMPT | |
| SCHEMBL8551329 | 0.87 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTHTTNAMPT | |
| SCHEMBL8479757 | 0.84 | POLB (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL8479934 | 0.82 | ADRB1 (0.45) | ALDH1A1NAMPTMEN1KMT2AADRB1 | |
| SCHEMBL7964059 | 0.81 | CYP3A4 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL8477139 | 0.81 | ALOX5 (0.49) | SMN1; SMN2ALDH1A1LMNANAMPTMEN1 | |
| SCHEMBL8480213 | 0.81 | ALOX5 (0.49) | SMN1; SMN2ALDH1A1LMNANAMPTMEN1 | |
| SCHEMBL7963443 | 0.81 | CYP3A4 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL7954714 | 0.81 | TBXAS1 (0.49) | ALDH1A1NAMPTMEN1KMT2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |