Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476796 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8481177 | 0.87 | SMN1; SMN2 (0.51) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8551036 | 0.87 | SMN1; SMN2 (0.51) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8479757 | 0.86 | POLB (0.52) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8479934 | 0.84 | ADRB1 (0.45) | ALDH1A1NAMPTF9F10ADRB1 | |
| SCHEMBL7964059 | 0.83 | CYP3A4 (0.52) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8477139 | 0.83 | ALOX5 (0.49) | ALDH1A1LMNANAMPTF9F10 | |
| SCHEMBL7963443 | 0.83 | CYP3A4 (0.52) | ALDH1A1MAPTLMNAHTTNAMPT | |
| SCHEMBL8480213 | 0.83 | ALOX5 (0.49) | ALDH1A1LMNANAMPTF9F10 | |
| SCHEMBL7771955 | 0.83 | CA2 (0.44) | NAMPTADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |