Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553727 | 0.89 | FFAR1 (0.47) | MAPK1MEN1KMT2ALMNAALOX5 | |
| SCHEMBL8109544 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2SLC6A2CYP2C19SLC6A3 | |
| SCHEMBL8551523 | 0.85 | CYP17A1 (0.47) | KMT2ALMNAL3MBTL1SMN1; SMN2SLC6A2 | |
| SCHEMBL8551928 | 0.82 | CYP11B1 (0.43) | MAPK1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7773934 | 0.82 | SLC6A4 (0.42) | KMT2ALMNAL3MBTL1SMN1; SMN2SLC6A2 | |
| SCHEMBL7772046 | 0.82 | SLC6A4 (0.42) | KMT2ALMNAL3MBTL1SMN1; SMN2SLC6A2 | |
| SCHEMBL8552624 | 0.81 | CYP19A1 (0.47) | SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8133883 | 0.79 | CYP17A1 (0.40) | LMNAL3MBTL1SMN1; SMN2SLC6A2CYP2C19 | |
| SCHEMBL8550029 | 0.78 | CYP19A1 (0.47) | CYP2C19 | |
| SCHEMBL8552479 | 0.78 | PRKCI (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |