Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197371 | 0.84 | NPC1 (0.49) | CNR2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL8708853 | 0.84 | CNR2 (0.41) | CNR2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL8550370 | 0.83 | KDM4E (0.41) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8546895 | 0.77 | MEN1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8551287 | 0.74 | HPGD (0.42) | HPGDNPC1RAB9AKMT2A | |
| Hexanoate SCHEMBL8550591 | 0.72 | CNR2 (0.39) | CNR2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL6669755 | 0.70 | HTR1F (0.45) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL7145054 | 0.67 | KMT2A (0.41) | ALDH1A1MEN1KMT2AHTTRECQL | |
| SCHEMBL8548267 | 0.67 | KDM4E (0.41) | ALDH1A1MEN1KMT2AHTTRECQL | |
| SCHEMBL8550531 | 0.67 | EGFR (0.42) | HPGDNPC1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |