Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145054 | 0.84 | KMT2A (0.41) | KDM4EGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8548267 | 0.84 | KDM4E (0.41) | KDM4EGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8551076 | 0.83 | CNR2 (0.41) | KMT2AALDH1A1MEN1RECQLHTT | |
| SCHEMBL8546895 | 0.82 | MEN1 (0.43) | KDM4EGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8552755 | 0.81 | KDM4E (0.43) | KDM4EGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8550959 | 0.76 | KDM4E (0.39) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL8553359 | 0.74 | HIF1A (0.42) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8551238 | 0.72 | ROCK1 (0.37) | KDM4EGAAALDH1A1MAPTRAD52 | |
| SCHEMBL8550531 | 0.71 | EGFR (0.42) | KDM4EGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6669755 | 0.69 | HTR1F (0.45) | KMT2AALDH1A1HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |