Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872083 | 0.81 | L3MBTL1 (0.67) | LTA4HSIGMAR1L3MBTL1SLC6A3GAA | |
| SCHEMBL8325936 | 0.78 | L3MBTL1 (0.62) | SIGMAR1HRH3L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL83687 | 0.74 | SIGMAR1 (0.86) | LTA4HSIGMAR1GRIN2BHRH3SLC6A3 | |
| SCHEMBL12593804 | 0.74 | INMT (0.46) | HRH3SMN1; SMN2POLB | |
| SCHEMBL8882276 | 0.74 | L3MBTL1 (0.57) | SIGMAR1GRIN2BL3MBTL1SLC6A3GAA | |
| SCHEMBL17117358 | 0.73 | SIGMAR1 (0.56) | LTA4HSIGMAR1GRIN2BSLC6A3POLB | |
| SCHEMBL8321647 | 0.73 | L3MBTL1 (0.55) | SIGMAR1HRH3L3MBTL1GAASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28704893 | 0.73 | SIGMAR1 (0.83) | LTA4HSIGMAR1GRIN2BHRH3SLC6A3 | |
| SCHEMBL20382580 | 0.73 | LTA4H (0.86) | LTA4HSIGMAR1GRIN2BHRH3SLC6A3 | |
| Hydrochloric Acid SCHEMBL8037018 | 0.73 | SIGMAR1 (0.83) | LTA4HSIGMAR1GRIN2BHRH3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | claimed |