SCHEMBL1808600

SCHEMBL1808600

CCOC(=O)c1sc(S)nc1C

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
HPGD P15428 3/20 0.58
HSD17B10 Q99714 1/20 0.55
CDC7 O00311 1/20 0.54
DBF4 Q9UBU7 1/20 0.54
NPC1 O15118 2/20 0.52
KDM4E B2RXH2 6/20 0.51
MAPT P10636 5/20 0.51
RAB9A P51151 1/20 0.51
LMNA P02545 3/20 0.50
TSHR P16473 1/20 0.50
CYP1A2 P05177 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
DHODH Q02127 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18558816 0.84 ALDH1A1 (0.66) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL7023549 0.81 RAB9A (0.50) ALDH1A1HPGDHSD17B10NPC1KDM4E
SCHEMBL12034449 0.81 CDC7 (0.69) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL2498385 0.81 NPC1 (0.72) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL27899564 0.80 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL288785 0.80 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL8555889 0.79 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL2720481 0.79 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL4287380 0.79 NPC1 (0.56) ALDH1A1HPGDHSD17B10CDC7DBF4
SCHEMBL244752 0.79 ALDH1A1 (0.73) ALDH1A1HPGDHSD17B10CDC7DBF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114609074-A Method for detecting content of cyclic amine compound in copper etching solution 江苏和达电子科技有限公司 2022-06-10 CN claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3947459-A FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-03-30 US claimed
CN-114609074-A Method for detecting content of cyclic amine compound in copper etching solution 江苏和达电子科技有限公司 2022-06-10 CN disclosed
EP-1801108-B9 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2013-11-20 EP disclosed
EP-1801108-B1 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2012-11-14 EP disclosed
US-7947683-B2 3-(1,2,4-triazol-3-ylalkyl) azabicyclo (3.1.0) hexane derivatives as modulators of dopamine D3 receptors GLAXO GROUP LIMTED (GB) 2011-05-24 US disclosed
US-7947683-B2 3-(1,2,4-triazol-3-ylalkyl) azabicyclo (3.1.0) hexane derivatives as modulators of dopamine D3 receptors GLAXO GROUP LIMTED (GB) 2011-05-24 US disclosed
US-7935700-B2 Morpholine compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-05-03 US disclosed
US-20090124629-A1 3-(1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2009-05-14 US disclosed
US-20090124629-A1 3-(1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2009-05-14 US disclosed
US-4705738-A Silver halide photographic material for tanning development and process of producing a relief image MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-10 US disclosed
EP-0195327-A2 Silver halide photographic material for tanning development and process of producing a relief image MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
EP-0194572-A1 Heterocyclic sulfides, process for their preparation and Medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1986-09-17 EP disclosed
US-4496683-A INCREASED SCORCH DELAY, FASTER CURE RATE AND IMPROVED REVERSION RESISTANCE MONSANTO COMPANY (US) 1985-01-29 US disclosed
EP-0104157-A1 Rubber compositions containing a vulcanization system alterative Monsanto Company (US) 1984-03-28 EP disclosed
US-4013638-A VULCANIZATION ACCELERATORS, OXIDATION INHIBITORS OF RUBBER MONSANTO COMPANY (US) 1977-03-22 US disclosed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US disclosed
US-3979369-A DIENE POLYMER MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3947459-A FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124629-A1 3-(1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS DRD3, HTR3C, TACR2 ALDH1A1 2591/4885HPGD 2051/4885HSD17B10 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.