Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | GFER | P55789 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550241 | 0.81 | ALDH1A1 (0.50) | GAAHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8543834 | 0.79 | ALDH1A1 (0.40) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8545040 | 0.78 | GABRP (0.39) | MEN1KMT2AGFERGAAALDH1A1 | |
| SCHEMBL8545303 | 0.75 | KDM4E (0.43) | MEN1KMT2AGFERGAAHTT | |
| SCHEMBL8549989 | 0.75 | PPARD (0.33) | MEN1KMT2APTGDR2PPARGPPARD | |
| SCHEMBL8546652 | 0.74 | PTGDR2 (0.34) | MEN1KMT2AGFERGAAALDH1A1 | |
| SCHEMBL8548816 | 0.74 | POLB (0.53) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11588944 | 0.73 | MAPT (0.43) | MEN1KMT2AGFERGAAALDH1A1 | |
| SCHEMBL8551360 | 0.72 | ALDH1A1 (0.46) | GAAALDH1A1KDM4EMAPTPTGDR2 | |
| SCHEMBL4481950 | 0.71 | PTGDR2 (0.42) | MEN1KMT2AGFERGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |