Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035936 | 0.89 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAEGLN1TP53 | |
| SCHEMBL8545303 | 0.87 | KDM4E (0.43) | ALDH1A1SMN1; SMN2GAAEGLN1KDM4E | |
| SCHEMBL8545040 | 0.83 | GABRP (0.39) | ALDH1A1GAAKDM4E | |
| SCHEMBL8548084 | 0.83 | PPARD (0.39) | ALDH1A1TP53KDM4E | |
| SCHEMBL8546674 | 0.82 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2GAAEGLN1TP53 | |
| SCHEMBL8546652 | 0.81 | PTGDR2 (0.34) | ALDH1A1GAAKDM4E | |
| SCHEMBL8551237 | 0.81 | MEN1 (0.32) | ALDH1A1SMN1; SMN2GAAKDM4EHTT | |
| SCHEMBL8544938 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAATP53KDM4EHTT | |
| SCHEMBL8545353 | 0.79 | KDM4E (0.45) | ALDH1A1SMN1; SMN2TP53KDM4ENPC1 | |
| SCHEMBL8546712 | 0.78 | L3MBTL1 (0.45) | ALDH1A1SMN1; SMN2TP53KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |