Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548778 | 0.81 | KMT2A (0.47) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL8553148 | 0.79 | PLAU (0.42) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL8553138 | 0.77 | POLB (0.37) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL8548686 | 0.76 | LRRK2 (0.49) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL8548608 | 0.75 | MAPT (0.44) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL9807627 | 0.74 | METAP1 (0.47) | ALDH1A1KDM4ETDP1POLBNPC1 | |
| SCHEMBL16387910 | 0.73 | PDE10A (0.50) | ALDH1A1KMT2AKDM4EMEN1POLB | |
| SCHEMBL4150422 | 0.72 | PDE10A (0.53) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL30117516 | 0.72 | PDE10A (0.53) | ALDH1A1KMT2AKDM4EMEN1TDP1 | |
| SCHEMBL5006757 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |