Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NSUN3 | Q9H649 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8550910 | 0.84 | ABCG2 (0.39) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL8552276 | 0.80 | KDR (0.43) | POLBNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8553148 | 0.78 | PLAU (0.42) | POLBNPC1F12ALDH1A1KMT2A | |
| SCHEMBL8551326 | 0.77 | ALDH1A1 (0.44) | POLBNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8552963 | 0.71 | ADORA2A (0.39) | NPC1MAPTNPSR1RAB9ARXFP1 | |
| SCHEMBL8548686 | 0.69 | LRRK2 (0.49) | POLBNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL16387910 | 0.66 | PDE10A (0.50) | POLBNPC1F12ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8546714 | 0.66 | MEN1 (0.45) | NPC1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4150422 | 0.66 | PDE10A (0.53) | POLBNPC1F12ALDH1A1KMT2A | |
| SCHEMBL30117516 | 0.66 | PDE10A (0.53) | POLBNPC1F12ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |