Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548648 | 0.89 | FAAH (0.47) | GPR119FAAHKDM4EPKMPTPN2 | |
| SCHEMBL8550086 | 0.83 | ALDH1A1 (0.42) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL8549754 | 0.83 | SMYD3 (0.45) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL8550973 | 0.80 | GPR119 (0.51) | GPR119ALDH1A1PTPN2PTPN1PTPN6 | |
| SCHEMBL23012615 | 0.79 | KDM4E (0.48) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL23012422 | 0.77 | GPR119 (0.44) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL24791688 | 0.75 | KDM4E (0.48) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL1698854 | 0.74 | GPR119 (0.57) | GPR119FAAHKDM4EPKMALDH1A1 | |
| SCHEMBL25212200 | 0.74 | GPR119 (0.46) | GPR119ALDH1A1 | |
| SCHEMBL25616980 | 0.74 | GPR119 (0.46) | GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |