Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551343 | 0.83 | GPR119 (0.48) | ALDH1A1FAAHGPR119KDM4EPKM | |
| SCHEMBL8548648 | 0.81 | FAAH (0.47) | FAAHGPR119KDM4EPKMPTPN2 | |
| SCHEMBL8549754 | 0.76 | SMYD3 (0.45) | ALDH1A1FAAHL3MBTL1MAPTMAPK1 | |
| SCHEMBL31657251 | 0.74 | KDM4E (0.46) | ALDH1A1FAAHL3MBTL1NPC1MAPT | |
| SCHEMBL4360565 | 0.74 | CHRM2 (0.52) | ALDH1A1L3MBTL1NPC1MAPTMAPK1 | |
| SCHEMBL7360145 | 0.74 | ALDH1A1 (0.42) | ALDH1A1FAAHL3MBTL1NPC1MAPT | |
| SCHEMBL25329388 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1NPC1MAPTMAPK1 | |
| SCHEMBL7340706 | 0.73 | GPR119 (0.51) | ALDH1A1GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL8549340 | 0.70 | GPR119 (0.40) | ALDH1A1FAAHL3MBTL1GPR119ABL1 | |
| SCHEMBL7367257 | 0.69 | KDM4E (0.47) | ALDH1A1FAAHL3MBTL1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |