Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551343 | 0.89 | GPR119 (0.48) | FAAHGPR119KDM4EPKMPTPN2 | |
| SCHEMBL8550086 | 0.81 | ALDH1A1 (0.42) | FAAHGPR119KDM4EPKMPTPN2 | |
| SCHEMBL8549754 | 0.81 | SMYD3 (0.45) | FAAHGPR119KDM4EPKMPTPN2 | |
| SCHEMBL8623093 | 0.79 | GPR119 (0.49) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL948286 | 0.74 | FAAH (0.49) | FAAHGPR119KDM4EPKMPTPN2 | |
| SCHEMBL23273843 | 0.73 | P2RX7 (0.47) | FAAHGPR119KDM4EPKM | |
| SCHEMBL21316494 | 0.73 | FAAH (0.47) | FAAHGPR119KDM4EPKM | |
| SCHEMBL1698618 | 0.73 | GPR119 (0.56) | FAAHGPR119KDM4EPKM | |
| SCHEMBL21722971 | 0.73 | GPR119 (0.46) | FAAHGPR119KDM4EPKM | |
| SCHEMBL948342 | 0.72 | GPR119 (0.52) | FAAHGPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |