Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471323 | 0.96 | LMNA (0.36) | KMT2AMEN1LMNAMAPTNPC1 | |
| SCHEMBL8555598 | 0.91 | SIRT2 (0.43) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL7465812 | 0.90 | TSHR (0.41) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL7470317 | 0.89 | TSHR (0.38) | HTTXIAPTSHR | |
| SCHEMBL8556732 | 0.88 | SIRT2 (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7462732 | 0.88 | TSHR (0.37) | HTTXIAPTSHR | |
| SCHEMBL8551158 | 0.86 | TSHR (0.38) | LMNAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8555937 | 0.86 | TSHR (0.48) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8643936 | 0.84 | MAOB (0.43) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8555223 | 0.83 | LMNA (0.36) | KMT2AMEN1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |