Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555937 | 0.92 | TSHR (0.48) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8555223 | 0.90 | LMNA (0.36) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL7465812 | 0.89 | TSHR (0.41) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8557722 | 0.86 | GSK3B (0.45) | TSHRLMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8555598 | 0.82 | SIRT2 (0.43) | TSHRMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8551162 | 0.82 | TSHR (0.39) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8595841 | 0.80 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8552816 | 0.78 | PPARG (0.46) | XIAP | |
| SCHEMBL8556732 | 0.78 | SIRT2 (0.41) | TSHRMAPTALDH1A1SMN1; SMN2SIRT2 | |
| SCHEMBL8550235 | 0.77 | TSHR (0.49) | TSHRALDH1A1XIAPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |