Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 11/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555598 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8557722 | 0.90 | GSK3B (0.45) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8595841 | 0.89 | TSHR (0.44) | ALDH1A1SMN1; SMN2TSHRPPARG | |
| SCHEMBL8551399 | 0.88 | KMT2A (0.36) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7470317 | 0.87 | TSHR (0.38) | TSHRPPARG | |
| Hydrochloric Acid SCHEMBL7462732 | 0.86 | TSHR (0.37) | TSHRPPARG | |
| SCHEMBL8552816 | 0.82 | PPARG (0.46) | PPARG | |
| SCHEMBL8556736 | 0.80 | SIRT2 (0.41) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7465812 | 0.79 | TSHR (0.41) | ALDH1A1SMN1; SMN2TSHRKMT2AMAPT | |
| SCHEMBL7473595 | 0.75 | SIRT2 (0.50) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |