Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465812 | 0.95 | TSHR (0.41) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8551158 | 0.92 | TSHR (0.38) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8555223 | 0.90 | LMNA (0.36) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8557722 | 0.81 | GSK3B (0.45) | TSHRLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8555598 | 0.80 | SIRT2 (0.43) | TSHRMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8595841 | 0.80 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7478778 | 0.78 | TSHR (0.64) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8556732 | 0.78 | SIRT2 (0.41) | TSHRMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7465815 | 0.77 | TSHR (0.40) | TSHRLMNAUSP2MAPK1ATM | |
| SCHEMBL8553542 | 0.76 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |