Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556732 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1TSHRALDH1A1KMT2A | |
| SCHEMBL8551399 | 0.91 | KMT2A (0.36) | SIRT2SIRT1TSHRALDH1A1HPGD | |
| SCHEMBL8557722 | 0.86 | GSK3B (0.45) | SIRT2SIRT1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7470317 | 0.85 | TSHR (0.38) | TSHRHTTPPARG | |
| Hydrochloric Acid SCHEMBL7462732 | 0.84 | TSHR (0.37) | TSHRHTTPPARG | |
| SCHEMBL8595841 | 0.84 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8551158 | 0.82 | TSHR (0.38) | SIRT2SIRT1TSHRALDH1A1HTT | |
| SCHEMBL8552816 | 0.81 | PPARG (0.46) | PPARG | |
| SCHEMBL7465812 | 0.81 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8555600 | 0.81 | SIRT2 (0.43) | SIRT2SIRT1TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |