SCHEMBL8551486

SCHEMBL8551486

Clc1cc(Cl)nc(OCc2ccsc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 6/20 0.43
PARP15 Q460N3 1/20 0.39
PARP10 Q53GL7 1/20 0.39
PARP3 Q9Y6F1 1/20 0.39
NPC1 O15118 2/20 0.39
FLT1 P17948 1/20 0.35
KDR P35968 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
IDO1 P14902 1/20 0.35
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
GABRA1 P14867 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRB1 P18505 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8546425 0.85 GRM5 (0.42) GRM5PARP15PARP10PARP3FLT1
SCHEMBL8549282 0.83 PARP15 (0.39) GRM5PARP15PARP10PARP3NPC1
SCHEMBL8547120 0.82 GRM5 (0.38) GRM5PARP15PARP10PARP3FLT1
SCHEMBL8550364 0.82 GRM5 (0.38) GRM5PARP15PARP10PARP3FLT1
SCHEMBL8546238 0.82 GRM5 (0.64) GRM5PARP15PARP10PARP3
SCHEMBL8546508 0.82 GRM5 (0.38) GRM5PARP15PARP10PARP3NPC1
SCHEMBL8549682 0.82 GRM5 (0.37) GRM5PARP15PARP10PARP3FLT1
SCHEMBL8551819 0.80 CYP11B1 (0.41) GRM5PARP15PARP10PARP3NPC1
SCHEMBL8550799 0.74 L3MBTL1 (0.45) L3MBTL1MAPT
SCHEMBL8547127 0.73 PARP15 (0.35) GRM5PARP15PARP10PARP3FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693490-B1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA CHEMICAL IND CO LTD (JP) 1998-09-09 EP disclosed
US-5624942-A 2-phenoxy-6-thienylmethyloxypyridine derivative and herbicidal composition containing same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-04-29 US disclosed
EP-0693490-A1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-24 EP disclosed