Sugi Predict

Sugi Predict / Compounds / SCHEMBL8551553

SCHEMBL8551553

SCHEMBL8551553

CNC(=C[N+](=O)[O-])NCC1CCOC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ SLC22A1 O15245 1/20 0.37
▸ ABCB11 O95342 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CHRM2 P08172 1/20 0.37
▸ CHRM1 P11229 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ ADRA2C P18825 1/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ CHRM3 P20309 1/20 0.37
▸ ATP4A P20648 1/20 0.37
▸ PTGS1 P23219 1/20 0.37
▸ HRH2 P25021 1/20 0.37
▸ SLC6A4 P31645 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ PTGS2 P35354 1/20 0.37
▸ ATP4B P51164 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8551550 1.00 ACHE (0.37) ACHEMEN1SLC22A1ABCB11LMNA
SCHEMBL8547465 0.88 BCHE (0.33) NAMPT
SCHEMBL8547468 0.88 BCHE (0.33) NAMPT
SCHEMBL8544397 0.80 ALDH1A1 (0.38) LMNAMAPTNAMPT
SCHEMBL8544399 0.80 ALDH1A1 (0.38) LMNAMAPTNAMPT
SCHEMBL8545760 0.80 NAMPT (0.31) NAMPT
SCHEMBL8545753 0.80 NAMPT (0.31) NAMPT
SCHEMBL8546125 0.77 — —
SCHEMBL8545424 0.75 KEAP1 (0.47) MEN1LMNAKMT2AMAPT
Dinotefuran SCHEMBL26337 0.75 NAMPT (0.34) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3324955-B1 COMPOSITION COMPRISING FIPRONIL AND DINOTEFURAN FOR USE IN AMETHOD OF CONTROLLING FLEAS IN NON HUMAN MAMMALS CEVA SANTE ANIMALE (FR) 2026-04-29 — — EP disclosed
US-11134685-B2 Compositions and uses thereof for controlling ectoparasites in non-human mammals Ceva Santé Animale (FR) 2021-10-05 — — US disclosed
EP-3358953-B1 VETERINARY COMPOSITIONS FOR THE CONTROL OF PHLEBOTOMES CEVA SANTE ANIMALE (FR) 2021-05-19 — — EP disclosed
US-10952988-B2 Methods for controlling the spread of dirofilariosis Ceva Santé Animale (FR) 2021-03-23 — — US disclosed
US-20200163339-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Santé Animale (FR) 2020-05-28 — — US disclosed
US-20180279620-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL CEVA SANTE ANIMALE (FR) 2018-10-04 — — US disclosed
US-20180235926-A1 METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS Ceva Santè Animale (FR) 2018-08-23 — — US disclosed
US-20180213790-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Santé Animale (FR) 2018-08-02 — — US disclosed
EP-3324955-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS Ceva Sante Animale (FR) 2018-05-30 — — EP disclosed
EP-3259990-A1 METHODS FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Sante Animale (FR) 2017-12-27 — — EP disclosed
WO-2017108904-A1 METHODS AND MEANS FOR THE ERADICATION OF FLEAS CEVA SANTE ANIMALE (FR) 2017-06-29 — — WO disclosed
EP-3183968-A1 METHODS AND MEANS FOR THE ERADICATION OF FLEAS Ceva Sante Animale (FR) 2017-06-28 — — EP disclosed
WO-2017060641-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL CEVA SANTE ANIMALE (FR) 2017-04-13 — — WO disclosed
WO-2017017021-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS CEVA SANTE ANIMALE (FR) 2017-02-02 — — WO disclosed
EP-3120846-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS Ceva Sante Animale (FR) 2017-01-25 — — EP disclosed
EP-0649845-B1 Furanyl insecticide MITSUI CHEMICALS INC (JP) 1998-07-22 — — EP disclosed
US-5532365-A NITROGUANIDINE COMPOUNDS AS INSECTICIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-02 — — US disclosed
US-5434181-A FOR USE IN AGRICULTURAL CHEMICALS MITSUI TOATSU CHEMICALS, INC. (JP) 1995-07-18 — — US disclosed
EP-0649845-A1 Furanyl insecticide MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-04-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11134685-B2 Compositions and uses thereof for controlling ectoparasites in non-human mammals NISCH, NAMPT, TYR ACHE 765/4885MEN1 3314/4885SLC22A1 4487/4885
US-20180235926-A1 METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS NISCH, DDT, TNNT2 ACHE 816/4885MEN1 3382/4885SLC22A1 3860/4885
US-10952988-B2 Methods for controlling the spread of dirofilariosis NISCH, DDT, TNNT2 ACHE 816/4885MEN1 3382/4885SLC22A1 3860/4885
US-20180279620-A1 VETERINARY COMPOSITIONS FOR SANDFLY CONTROL NISCH, SGMS1, SGMS2 ACHE 691/4885MEN1 3813/4885SLC22A1 1788/4885
US-20180213790-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS NISCH, NAMPT, TYR ACHE 765/4885MEN1 3314/4885SLC22A1 4487/4885
US-20200163339-A1 COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS NISCH, NAMPT, TYR ACHE 765/4885MEN1 3314/4885SLC22A1 4487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.