Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557456 | 0.89 | LMNA (0.48) | LMNASMN1; SMN2PDE3BPDE3AHTT | |
| SCHEMBL8553605 | 0.87 | ALOX5 (0.48) | LMNASMN1; SMN2PDE3BPDE3AHTT | |
| SCHEMBL8551585 | 0.85 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2PDE3BPDE3AHTT | |
| SCHEMBL8557469 | 0.80 | PDE3B (0.52) | LMNASMN1; SMN2PDE3BPDE3AALOX5 | |
| SCHEMBL8551933 | 0.79 | PDE3B (0.51) | LMNASMN1; SMN2PDE3BPDE3AALOX5 | |
| SCHEMBL8555588 | 0.78 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2PDE3BPDE3AHTT | |
| SCHEMBL8554409 | 0.77 | LMNA (0.47) | LMNASMN1; SMN2PDE3BPDE3AALOX5 | |
| SCHEMBL8554381 | 0.77 | PDE3B (0.48) | LMNASMN1; SMN2PDE3BPDE3AALOX5 | |
| SCHEMBL7707823 | 0.76 | ALOX5 (0.44) | LMNASMN1; SMN2PDE3BPDE3AHTT | |
| SCHEMBL8557542 | 0.74 | LMNA (0.42) | LMNASMN1; SMN2PDE3BPDE3AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572001-B1 | Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components | MITSUI CHEMICALS INC (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5530146-A | TETRAHYDROFURAN DERIVATIVE INTERMEDIATES | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5356866-A | Completely selective to crops such as paddy rice, soybeans and cotton | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0572001-A1 | Furobenzopyran derivatives, process for preparation of same and herbicides containing same as active components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-01 | — | — | EP | disclosed |