Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554342 | 0.77 | NTRK1 (0.51) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL8555685 | 0.77 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10CASP1TSHR | |
| SCHEMBL8559433 | 0.75 | LRRK2 (0.46) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8551978 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8554132 | 0.73 | GAA (0.48) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8553162 | 0.70 | GAA (0.45) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL10706449 | 0.67 | ACHE (0.62) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7519805 | 0.67 | KMT2A (0.59) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL5549334 | 0.67 | MEN1 (0.68) | TSHRGAAPOLBMEN1KMT2A | |
| SCHEMBL6445232 | 0.67 | ACHE (0.56) | ALDH1A1KDM4EHPGDHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |