Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 6/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553324 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8550649 | 0.83 | NTRK1 (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8554394 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8551939 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8552117 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8556539 | 0.66 | MAPT (0.42) | ALDH1A1SMN1; SMN2L3MBTL1NTRK1MAPT | |
| SCHEMBL8553151 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL8553146 | 0.65 | NTRK1 (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2NTRK1 | |
| SCHEMBL22281749 | 0.61 | TDP1 (0.48) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL854938 | 0.61 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |