Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.42 |
| ▸ | ITGAV | P06756 | 10/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553819 | 0.86 | KCNA5 (0.45) | ITGB3ITGAVKCNA5SUCNR1ITGA2B | |
| SCHEMBL8554522 | 0.82 | KCNA5 (0.42) | KCNA5SUCNR1CTSLCTSSCTSK | |
| SCHEMBL8555195 | 0.74 | KCNA5 (0.45) | KCNA5SUCNR1CTSLCTSSCTSK | |
| SCHEMBL8553452 | 0.72 | SUCNR1 (0.41) | SUCNR1 | |
| SCHEMBL8552369 | 0.72 | EPHX1 (0.45) | KCNA5SUCNR1CTSLCTSSCTSK | |
| SCHEMBL8118468 | 0.69 | KCNA5 (0.45) | KCNA5SUCNR1TRPM8 | |
| SCHEMBL8483450 | 0.69 | MAPT (0.41) | — | |
| SCHEMBL8477180 | 0.69 | MAPT (0.41) | — | |
| SCHEMBL8552254 | 0.68 | SUCNR1 (0.50) | ITGB3ITGAVKCNA5SUCNR1ITGA2B | |
| SCHEMBL8551344 | 0.68 | CYP19A1 (0.47) | SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |