Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552369 | 0.87 | EPHX1 (0.45) | KCNA5SUCNR1FFAR1CTSLCTSS | |
| SCHEMBL8118468 | 0.87 | KCNA5 (0.45) | KCNA5SUCNR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8551344 | 0.86 | CYP19A1 (0.47) | SUCNR1ALDH1A1 | |
| SCHEMBL8549826 | 0.86 | KCNA5 (0.43) | KCNA5FFAR1PSEN1PSEN2APH1B | |
| SCHEMBL8556196 | 0.85 | PDE4D (0.41) | ALDH1A1LMNAMAPT | |
| SCHEMBL8553713 | 0.83 | CYP17A1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8553452 | 0.82 | SUCNR1 (0.41) | SUCNR1USP2NPSR1LMNAMAPT | |
| SCHEMBL8552076 | 0.82 | ITGB3 (0.42) | KCNA5SUCNR1MMEACEPSEN1 | |
| SCHEMBL8550686 | 0.78 | KCNA5 (0.43) | KCNA5SUCNR1SLC6A4 | |
| SCHEMBL8555638 | 0.76 | SUCNR1 (0.43) | KCNA5SUCNR1FFAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |