Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552369 | 0.85 | EPHX1 (0.45) | SUCNR1ADRB3ADRB1HTTAKR1C3 | |
| SCHEMBL8554522 | 0.82 | KCNA5 (0.42) | SUCNR1LMNAMKNK1MKNK2USP2 | |
| SCHEMBL8549826 | 0.76 | KCNA5 (0.43) | — | |
| SCHEMBL8551344 | 0.76 | CYP19A1 (0.47) | SUCNR1 | |
| SCHEMBL8556196 | 0.76 | PDE4D (0.41) | LMNAMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8555243 | 0.74 | AKR1C3 (0.41) | SUCNR1ADRB3ADRB1MKNK1MKNK2 | |
| SCHEMBL8553713 | 0.74 | CYP17A1 (0.42) | LMNAADRB3ADRB1MAPT | |
| SCHEMBL8552076 | 0.72 | ITGB3 (0.42) | SUCNR1 | |
| SCHEMBL8550969 | 0.71 | EPHX1 (0.46) | ADRB3ADRB1HTTSMN1; SMN2 | |
| SCHEMBL8555184 | 0.70 | KCNA5 (0.40) | SMN1; SMN2RORCAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |