Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.41 |
| ▸ | ITGAV | P06756 | 10/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552076 | 0.86 | ITGB3 (0.42) | KCNA5ITGB3ITGAVSUCNR1ITGA2B | |
| SCHEMBL8118468 | 0.78 | KCNA5 (0.45) | KCNA5SUCNR1KDRTEKKCND3 | |
| SCHEMBL8550686 | 0.69 | KCNA5 (0.43) | KCNA5SUCNR1KCND3 | |
| Hydrochloric Acid SCHEMBL10664234 | 0.69 | KCNA5 (0.46) | KCNA5SUCNR1KDRTEK | |
| SCHEMBL8552254 | 0.68 | SUCNR1 (0.50) | KCNA5ITGB3ITGAVSUCNR1ITGA2B | |
| SCHEMBL8554522 | 0.68 | KCNA5 (0.42) | KCNA5SUCNR1CTSLCTSSCTSK | |
| SCHEMBL8592667 | 0.67 | CLK4 (0.41) | KCNA5KDRTEK | |
| SCHEMBL8479680 | 0.67 | CLK4 (0.41) | KCNA5KDRTEK | |
| SCHEMBL8555195 | 0.67 | KCNA5 (0.45) | KCNA5SUCNR1CTSLCTSSCTSK | |
| SCHEMBL551225 | 0.66 | CYP2A6 (0.62) | KCNA5KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |