Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553715 | 0.81 | NR1H2 (0.38) | MAPTNR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL8551148 | 0.77 | ENPP3 (0.38) | CA9MAPTSLC9A1ENPP3NR1H2 | |
| SCHEMBL8547668 | 0.74 | PLAU (0.37) | MAPTNR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL8552083 | 0.73 | MEN1 (0.34) | MAPTNR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL8550323 | 0.73 | PLG (0.42) | MAPTNR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL8548633 | 0.72 | PLG (0.41) | MAPTNR1H2NR1H3 | |
| SCHEMBL8553708 | 0.71 | LMNA (0.35) | CA9MAPTENPP3NR1H2NR1H3 | |
| SCHEMBL8551133 | 0.67 | NR1H2 (0.42) | MAPTNR1H2NR1H3 | |
| SCHEMBL8546417 | 0.66 | MEN1 (0.36) | MAPTSCN9ALMNASMN1; SMN2 | |
| SCHEMBL8554002 | 0.66 | PLAU (0.44) | MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |