Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553324 | 0.79 | KDM4E (0.43) | KDM4EHPGDALDH1A1LMNANTRK1 | |
| SCHEMBL8550649 | 0.79 | NTRK1 (0.46) | KDM4EHPGDALDH1A1LMNANTRK1 | |
| SCHEMBL8553095 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8553151 | 0.74 | KDM4E (0.43) | KDM4EHPGDALDH1A1LMNANTRK1 | |
| SCHEMBL8551978 | 0.73 | KDM4E (0.44) | KDM4EHPGDALDH1A1NTRK1MAPT | |
| SCHEMBL8553146 | 0.72 | NTRK1 (0.54) | KDM4EHPGDALDH1A1LMNANTRK1 | |
| SCHEMBL8555334 | 0.69 | MAPT (0.46) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL8553162 | 0.69 | GAA (0.45) | KDM4EHPGDALDH1A1LMNANTRK1 | |
| SCHEMBL23116826 | 0.67 | GAA (0.46) | KDM4EHPGDALDH1A1LMNAMAPT | |
| SCHEMBL2546236 | 0.67 | GAA (0.68) | KDM4EHPGDALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |