Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555334 | 0.89 | MAPT (0.46) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL8553385 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL8555849 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL8556539 | 0.83 | MAPT (0.42) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL1984012 | 0.79 | NTRK1 (0.48) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL8554394 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBHTTL3MBTL1 | |
| SCHEMBL8552117 | 0.78 | KDM4E (0.46) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL8552075 | 0.74 | FPR1 (0.41) | ALDH1A1MAPTLMNAFLT1FLT4 | |
| SCHEMBL8556278 | 0.74 | NTRK1 (0.43) | ALDH1A1MAPTPOLBHTTL3MBTL1 | |
| SCHEMBL8552895 | 0.74 | FPR1 (0.48) | ALDH1A1MAPTPOLBHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |