Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553324 | 0.89 | KDM4E (0.43) | NTRK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL8551978 | 0.83 | KDM4E (0.44) | NTRK1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL8556539 | 0.81 | MAPT (0.42) | NTRK1ALDH1A1LMNATSHRHTT | |
| SCHEMBL8552117 | 0.79 | KDM4E (0.46) | NTRK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL8554342 | 0.71 | NTRK1 (0.51) | NTRK1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL8553151 | 0.71 | KDM4E (0.43) | NTRK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL8553146 | 0.70 | NTRK1 (0.54) | NTRK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL8555849 | 0.69 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL8553385 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL2546236 | 0.65 | GAA (0.68) | ALDH1A1LMNAKDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |