Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8550910 | 0.89 | ABCG2 (0.39) | ALDH1A1NPSR1ENPP3MAPTTDP1 | |
| SCHEMBL8548358 | 0.81 | ALDH1A1 (0.46) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8553138 | 0.80 | POLB (0.37) | ALDH1A1NPSR1MAPTGAAHPGD | |
| SCHEMBL8553709 | 0.78 | ALDH1A1 (0.43) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8552284 | 0.78 | PLAU (0.40) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8547661 | 0.78 | ALDH1A1 (0.43) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8547920 | 0.77 | ALDH1A1 (0.64) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8548608 | 0.77 | MAPT (0.44) | ALDH1A1NPSR1MAPTTDP1KMT2A | |
| Hydrochloric Acid SCHEMBL8551921 | 0.71 | ALDH1A1 (0.46) | KDRALDH1A1NPSR1ENPP3MAPT | |
| SCHEMBL8547602 | 0.70 | NPSR1 (0.36) | KDRALDH1A1NPSR1ENPP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |