Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8550917 | 0.88 | PLAU (0.45) | PLAUMAPTPLGALDH1A1TDP1 | |
| SCHEMBL8548363 | 0.80 | PLAU (0.39) | PLAUKDRNPSR1MAPTPLG | |
| SCHEMBL8553148 | 0.79 | PLAU (0.42) | PLAUNPSR1PLGALDH1A1TDP1 | |
| SCHEMBL8548608 | 0.78 | MAPT (0.44) | NPSR1MAPTALDH1A1TDP1LMNA | |
| SCHEMBL8552276 | 0.78 | KDR (0.43) | KDRNPSR1MAPTALDH1A1TDP1 | |
| SCHEMBL8553714 | 0.77 | PLAU (0.37) | PLAUKDRNPSR1MAPTPLG | |
| SCHEMBL8547668 | 0.77 | PLAU (0.37) | PLAUKDRNPSR1MAPTPLG | |
| SCHEMBL8547926 | 0.76 | ALDH1A1 (0.51) | PLAUKDRNPSR1MAPTPLG | |
| SCHEMBL8547799 | 0.71 | KMT2A (0.43) | NPSR1MAPTALDH1A1TDP1LMNA | |
| Hydrochloric Acid SCHEMBL8549377 | 0.68 | PLG (0.55) | PLAUKDRNPSR1MAPTPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |