Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamide SCHEMBL4639002 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL8551071 | 0.77 | NTRK1 (0.41) | PTGS2NTRK1HPGDLMNAALDH1A1 | |
| SCHEMBL8140595 | 0.77 | MIF (0.43) | PTGS2PTGS1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL8908949 | 0.76 | ALOX5AP (0.40) | PTGS2PTGS1 | |
| SCHEMBL213239 | 0.76 | PTGS2 (0.56) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8552368 | 0.73 | ACLY (0.36) | PTGS2PTGS1NTRK1ACLYIMPDH2 | |
| SCHEMBL8147501 | 0.72 | PTGS2 (0.57) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8153075 | 0.71 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8146634 | 0.69 | MAOB (0.55) | PTGS2PTGS1TP53 | |
| SCHEMBL6250172 | 0.69 | MIF (0.43) | PTGS2PTGS1SMN1; SMN2HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |