Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552370 | 0.73 | PTGS2 (0.38) | ACLYNTRK1IMPDH2PTGS2PTGS1 | |
| SCHEMBL8551071 | 0.68 | NTRK1 (0.41) | SCN9ANTRK1PTGS2CFTR | |
| SCHEMBL8908949 | 0.67 | ALOX5AP (0.40) | PTGS2PTGS1CFTR | |
| SCHEMBL27820773 | 0.62 | CYP17A1 (0.48) | PTGS2 | |
| SCHEMBL8908994 | 0.59 | MAOB (0.47) | ACLYIMPDH2 | |
| SCHEMBL8659730 | 0.56 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8648029 | 0.56 | PTGS2 (0.59) | ACLYSCN9ANTRK1PTGS2PTGS1 | |
| SCHEMBL8640455 | 0.56 | PTGS2 (0.45) | SCN9APTGS2PTGS1 | |
| SCHEMBL31034763 | 0.55 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL3409662 | 0.55 | PTGS2 (0.73) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |