Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908949 | 0.85 | ALOX5AP (0.40) | CFTRCA2CA1CA12CA9 | |
| SCHEMBL8908994 | 0.82 | MAOB (0.47) | CA2CA1CA12CA9CA4 | |
| SCHEMBL8547875 | 0.75 | CA2 (0.45) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL6026444 | 0.72 | BRD4 (0.43) | CA2CA1CA12CA9CA4 | |
| SCHEMBL7408121 | 0.72 | HPGDS (0.44) | CA2CA1CA12CA9CA4 | |
| SCHEMBL6986037 | 0.71 | EDNRB (0.56) | HPGDSEDNRBEDNRA | |
| SCHEMBL8554062 | 0.71 | CA1 (0.44) | CA2CA1CA12CA9CA4 | |
| SCHEMBL7408116 | 0.70 | BRD4 (0.41) | CA2CA1CA12CA9CA4 | |
| Trifluoroacetic Acid SCHEMBL27977019 | 0.68 | PRSS1 (0.39) | NTRK1CA2CA1CA12CA9 | |
| SCHEMBL5822874 | 0.68 | PTGS2 (0.54) | CA2CA1CA12CA9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |