Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552401 | 0.85 | RORC (0.51) | RORCACKR3L3MBTL1HTR1AHTR1B | |
| SCHEMBL8552426 | 0.84 | RORC (0.49) | RORCACKR3L3MBTL1HTR1AHTR1B | |
| SCHEMBL7483530 | 0.84 | RORC (0.68) | RORCHTR1AHTR1BHTR1F | |
| SCHEMBL8708863 | 0.81 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL8703840 | 0.76 | UBE2M (0.44) | UBE2MDCUN1D1 | |
| Phenyl Propionic Acid SCHEMBL8552444 | 0.76 | UBE2M (0.46) | UBE2MDCUN1D1 | |
| SCHEMBL8553042 | 0.76 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL8553038 | 0.76 | UBE2M (0.42) | UBE2MDCUN1D1 | |
| SCHEMBL8550202 | 0.76 | UBE2M (0.40) | UBE2MDCUN1D1 | |
| SCHEMBL8547821 | 0.76 | HTR1D (0.44) | RORCHTR1AHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |